Intermittent claudication is a condition characterized by pain, cramping, or fatigue in the leg muscles during physical activity, such as walking, which is alleviated by resting. It is caused by a narrowing or blockage in the arteries that supply blood to the legs, which reduces the amount of oxygen and nutrients that reach the affected muscles. Intermittent claudication is usually a symptom of peripheral arterial disease (PAD), which is often caused by atherosclerosis or the buildup of plaque in the arteries. Other risk factors for PAD include smoking, diabetes, high blood pressure, and high cholesterol. Treatment options for intermittent claudication include lifestyle modifications (such as exercise and smoking cessation), medication, angioplasty, and surgery.
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